The Asokan Lab engineers biological macromolecules and viruses for human gene therapy. Our vision has evolved over the years from tackling complexity to seeking simplicity - from studying and engineering Adeno-Associated Viruses (AAV) to back-splicing and trans-splicing RNAs and most recently, designing new immunomodulatory and effector proteins. We pursue applications across a range of organs, tissues and cell types and our overarching goal is to amalgamate these platform technologies for clinical translation of genetic medicines.